Gideon M Hirschfield Selected Research

Aspartate Aminotransferases (Aspartate Transaminase)

12/2022	Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls.
6/2021	Multiparametric Magnetic Resonance Imaging, Autoimmune Hepatitis, and Prediction of Disease Activity.
2/2021	Obeticholic acid is associated with improvements in AST-to-platelet ratio index and GLOBE score in patients with primary biliary cholangitis.
9/2020	Real-World Effectiveness of Obeticholic Acid in Patients with Primary Biliary Cholangitis.
2/2016	Stratification of hepatocellular carcinoma risk in primary biliary cirrhosis: a multicentre international study.

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Gideon M Hirschfield Research Topics

Disease

62	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 02/2024 - 05/2008
33	Sclerosing Cholangitis 05/2024 - 01/2009
27	Liver Diseases (Liver Disease) 02/2024 - 01/2009
20	Pruritus (Itching) 02/2024 - 08/2010
17	Fibrosis (Cirrhosis) 05/2024 - 10/2010
15	Autoimmune Hepatitis 02/2024 - 01/2009
13	Inflammation (Inflammations) 01/2024 - 04/2004
11	Cholestasis 10/2023 - 06/2013
10	Autoimmune Diseases (Autoimmune Disease) 11/2019 - 05/2008
8	Disease Progression 01/2022 - 05/2011
8	Neoplasms (Cancer) 10/2020 - 02/2016
6	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 11/2022 - 01/2014
6	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021 - 01/2016
5	End Stage Liver Disease 01/2024 - 04/2016
4	Cholangitis 12/2020 - 06/2009
3	Alcoholic Fatty Liver 10/2023 - 11/2019
3	Hepatitis 05/2019 - 06/2015
2	Hemorrhage 01/2021 - 01/2019
2	Genetic Predisposition to Disease (Genetic Predisposition) 03/2019 - 01/2014
2	Fatigue 01/2019 - 08/2010
2	Immunoglobulin G4-Related Disease 01/2018 - 06/2014
2	Bile Duct Diseases (Bile Duct Disease) 01/2018 - 01/2017
2	Pathologic Constriction (Stenosis) 11/2017 - 06/2014
2	Hepatolenticular Degeneration (Wilson's Disease) 11/2017 - 06/2012
2	Necrosis 06/2016 - 04/2006
2	Chronic Hepatitis C 06/2015 - 02/2014
2	Infections 06/2015 - 02/2014
2	Atherosclerosis 01/2008 - 06/2005
2	Acute-Phase Reaction 06/2005 - 12/2003
1	Dysbiosis 02/2024
1	Non-alcoholic Fatty Liver Disease 01/2024
1	Skin Diseases (Skin Disease) 12/2023

Drug/Important Bio-Agent (IBA)

36	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 01/2023 - 01/2009
21	Alkaline PhosphataseIBA 05/2024 - 10/2010
15	Bile Acids and Salts (Bile Acids)IBA 02/2024 - 05/2011
14	Biomarkers (Surrogate Marker)IBA 05/2024 - 04/2010
11	BilirubinIBA 03/2024 - 06/2014
10	AntibodiesIBA 01/2021 - 05/2008
9	obeticholic acidIBA 12/2022 - 04/2015
7	seladelparIBA 02/2024 - 10/2017
7	AutoantibodiesIBA 11/2022 - 04/2010
7	Immunoglobulin G (IgG)IBA 04/2022 - 01/2009
6	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021 - 09/2011
5	bile acid binding proteinsIBA 07/2023 - 07/2016
5	Aspartate Aminotransferases (Aspartate Transaminase)IBA 12/2022 - 02/2016
4	Alanine Transaminase (SGPT)IBA 12/2022 - 04/2015
4	Interleukin-12 (IL 12)IBA 11/2018 - 06/2009
4	Proteins (Proteins, Gene)FDA Link 06/2013 - 02/2004
3	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 10/2023 - 10/2017
3	DNA (Deoxyribonucleic Acid)IBA 10/2020 - 06/2009
3	3- ((((3R,5R)- 3- butyl- 3- ethyl- 7- (methyloxy)- 1,1- dioxido- 5- phenyl- 2,3,4,5- tetrahydro- 1,4- benzothiazepin- 8- yl)methyl)amino)pentanedioic acidIBA 01/2019 - 07/2016
3	AntigensIBA 08/2018 - 01/2018
3	CholesterolIBA 06/2013 - 04/2004
3	EnzymesIBA 02/2012 - 12/2010
3	C-Reactive ProteinIBA 04/2006 - 04/2004
2	timolumabIBA 05/2024 - 01/2017
2	PPAR deltaIBA 12/2023 - 01/2022
2	AntipruriticsIBA 12/2023 - 08/2010
2	maralixibatIBA 01/2023 - 03/2019
2	SodiumIBA 01/2023 - 01/2017
2	Hormones (Hormone)IBA 06/2021 - 01/2019
2	aldaferminIBA 06/2021 - 01/2019
2	Protons (Proton)IBA 06/2021 - 01/2018
2	ParaffinIBA 10/2020 - 08/2018
2	Formaldehyde (Formol)FDA Link 10/2020 - 08/2018
2	AlbuminsIBA 09/2020 - 01/2019
2	Immunoglobulin M (IgM)IBA 09/2020 - 02/2012
2	sodium-bile acid cotransporterIBA 01/2020 - 03/2019
2	SteroidsIBA 12/2019 - 01/2014
2	Rifampin (Rifampicin)FDA LinkGeneric 01/2019 - 08/2010
2	Complement C3 (C3 Complement)IBA 01/2019 - 06/2005
2	Cholestyramine Resin (Questran)FDA LinkGeneric 01/2019 - 08/2010
2	CopperIBA 11/2017 - 06/2012
2	AcidsIBA 01/2017 - 04/2015
2	HLA Antigens (Human Leukocyte Antigens)IBA 01/2017 - 05/2016
2	LigandsIBA 06/2016 - 04/2006
2	Ribavirin (Virazole)FDA LinkGeneric 06/2015 - 02/2014
2	Immunoglobulins (Immunoglobulin)IBA 06/2015 - 05/2015
2	Vitamin D FDA LinkGeneric 07/2014 - 08/2010
2	Azathioprine (Imuran)FDA LinkGeneric 02/2012 - 01/2009
2	Apolipoproteins E (ApoE)IBA 01/2008 - 06/2005
2	ApolipoproteinsIBA 01/2008 - 06/2005
2	Acute-Phase Proteins (Acute-Phase Protein)IBA 01/2008 - 04/2006
2	Serum Amyloid P-ComponentIBA 06/2005 - 02/2004
1	Monoclonal AntibodiesIBA 05/2024
1	Small Cytoplasmic RNAIBA 01/2024
1	CytokinesIBA 12/2023
1	Prednisolone (Predate)FDA LinkGeneric 10/2023
1	BerberineIBA 11/2022
1	tropifexorIBA 11/2022
1	Transaminases (Aminotransferases)IBA 04/2022
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 06/2021
1	2- (2,6- dimethyl- 4- (3- (4- (methylthio)phenyl)- 3- oxo- 1- propenyl)phenoxyl)- 2- methylpropanoic acidIBA 01/2021
1	Budesonide (Pulmicort)FDA LinkGeneric 01/2021

Therapy/Procedure

42	Therapeutics 02/2024 - 01/2009
21	Liver Transplantation 01/2023 - 01/2009
5	Transplantation 01/2024 - 03/2012
2	Immunotherapy 01/2020 - 01/2015
2	Colectomy 01/2020 - 10/2016
2	Cholecystectomy 01/2020 - 01/2020